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|Minimum Order Quantity||500 Pack|
|Brand Preference||Sun Pharma|
|Type Of Medicines||Allopathic|
Budez CR capsules 3mg are used to treat mild to moderate Crohn's disease, which is a chronic inflammatory disease of the intestines and an autoimmune disease (when the immune system attacks self) that can cause inflammation at any point of the gastrointestinal system. Budez CR capsules can be used to treat Crohn's disease where it affects the ileum (last section of the small intestine) and/or the ascending colon (first section of the large intestine or bowel), which is the most common form of the disease. Budez CR capsules 3mg are used to induce remission and also for maintenance of remission to prevent flare up of symptoms. Budez CR can also be used to treat recurring active episodes and acute attacks as part of long-term treatment of Crohn's disease, to relieve symptoms caused by inflammation and ulceration of the intestine like abdominal pain, diarrhoea, bleeding from the rectum and fever.
Budez CR capsules 3mg contain budesonide, a synthetic glucocorticosteroid that has potent topical anti-inflammatory activity and is much more potent than cortisol, which is an endogenous (produced by the body) corticosteroid. Crohn's disease is characterised by migration of certain white cells (leucocytes) into the irritated intestinal tissue, where they release inflammatory chemicals like cytokines, prostaglandins and leukotrienes. Budesonide in Budez CR capsules 3mg binds to glucocorticosteroid receptor in the intestinal cells and inhibits the production of inflammatory cytokines and cytokine-mediated immune responses that are thought to be involved in Crohn's disease. Budez CR capsules 3mg are formulated to allow slow but prolonged local release of budesonide; the capsules are resistant to digestion by gastric juices and contain granules coated in a protective matrix which releases budesonide in a slow controlled manner in the ileum (last part of the small intestine) through the ascending colon (the first part of the large bowel). Although budesonide is absorbed into the blood it is rapidly metabolized and it does have some systemic effects (adrenocortical suppression), but they are very much less than other oral glucocorticoids like prednisolone, which means that the inhibition of naturally produced cortisol is minimal, as is the demineralization of bone and loss of bone mass that is caused by glucocorticoids like prednisolone.